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Loss of a paternal chromosome causes developmental anomalies among Drosophila hybrids
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  • Original Article
  • Published: 01 November 1992

Loss of a paternal chromosome causes developmental anomalies among Drosophila hybrids

  • John M Braverman1,
  • Beatriz Goñi2 &
  • H Allen Orr1 

Heredity volume 69, pages 416–422 (1992)Cite this article

  • 516 Accesses

  • 6 Citations

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Abstract

Hybrids between Drosophila virilis and D. lummei suffer from developmental anomalies. Previous reports also suggest that these hybrids lose the D. lummei sixth chromosome early in development. Genetic and cytological data presented here confirm the loss of the microchromosome from both the soma and the germ-line of these hybrids and provide strong evidence that this loss causes the hybrid developmental anomalies.

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References

  • Alexander, M L. 1976. The genetics of Drosophila virilis. In: Ashburner, M. and Novitski, E. (eds) The Genetics and Biology of Drosophila, Vol. 1c, Academic Press, London.

    Google Scholar 

  • Ashburner, M. 1989. Drosophila: a Laboratory Handbook. Cold Spring Harbor Laboratory Press, New York.

    Google Scholar 

  • Bennett, M D, Finch, R A, and Barclay, I R. 1976. The time rate and mechanism of chromosome elimination in Hordeum by hybrids. Chromosoma, 54, 175–200.

    Article  Google Scholar 

  • Von Bothmer, R, Salomon, B, and Linde-Laursen, I. 1991. Cytogenetics in hybrids of Hordeum jubatum and H. tetraploidium with cultivated barley (H. vulgare 1.). Hereditas, 114, 41–46.

    Article  Google Scholar 

  • Evgen'Ev, M B, and Sidorova, N V. 1976. Genetic regulation of chromosome behavior in interspecific hybrids of Drosophila. Theor Appl Gen, 48, 55–61.

    Article  CAS  Google Scholar 

  • Heikkinen, E. 1991. Wrinkling of the eye in hybrids between Drosophila virilis and Drosophila lummei is caused by interaction of maternal and zygotic genes. Heredity, 66, 357–365.

    Article  Google Scholar 

  • Imai, H T, Taylor, R W, Crosland, M W J, and Crozier, R H. 1988. Modes of spontaneous chromosomal mutation and karyotype evolution in ants with reference to the minimum interaction hypothesis. Jpn J Genet, 63, 159–185.

    Article  CAS  Google Scholar 

  • Lindsley, D L, and Grell, E H. 1968. Genetic Variations of Drosophila melanogaster. Carnegie Inst. Wash. Publ. 627. Washington, DC.

    Google Scholar 

  • Miklos, G L G, Yamamoto, M-T, Davies, J, and Pirrotta, V. 1988. Microcloning reveals a high frequency of repetitive sequences characteristic of chromosome 4 and the B-heterochromatin of Drosophila melanogaster. Proc Natl Acad Sci, USA, 85, 2051–2055.

    Article  CAS  Google Scholar 

  • Mitrofanov, V G, and Sidorova, N V. 1979. Phenogenetic analysis of chromosome behavior during mitosis in female Drosophila virilis × male Drosophila lummei hybrids. Soviet Genetics, 15, 807–811.

    Google Scholar 

  • Muller, H J. 1942. Recessive genes causing interspecific sterility and other disharmonies between Drosophila melanogaster and simulans. Genetics, 27, 157.

    Google Scholar 

  • Orr, H A. 1990. Developmental anomalies in Drosophila hybrids are apparently caused by loss of microchromosome. Heredity, 64, 255–262.

    Article  Google Scholar 

  • Sokolov, N N. 1948. Elimination of chromosomes in interspecific hybrids of Drosophila and the problems of distant hybrids. Dokladi Academii Nauk, 59, 163–166. (In Russian).

    Google Scholar 

  • Sokolov, N N. 1959. The interaction of nucleus and cytoplasm in distant hybrids. Moscow: Izdatelstvo Academii Nauk, 1–148 (In Russian).

  • Throckmorton, L H. 1982. The virilis species group. In: Ashburner, M., Carson, H. L. and Thompson, J. N. Jr. (eds) The Genetics and Biology of Drosophila. Vol. 3b, Academic Press, London, pp. 227–296.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Center for Population Biology, University of California, Davis, 95616, CA, USA

    John M Braverman & H Allen Orr

  2. Department of Genetics, University of California, Davis, 95616, CA, USA

    Beatriz Goñi

Authors
  1. John M Braverman
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  2. Beatriz Goñi
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  3. H Allen Orr
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Cite this article

Braverman, J., Goñi, B. & Orr, H. Loss of a paternal chromosome causes developmental anomalies among Drosophila hybrids. Heredity 69, 416–422 (1992). https://doi.org/10.1038/hdy.1992.145

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  • Received: 17 December 1991

  • Issue date: 01 November 1992

  • DOI: https://doi.org/10.1038/hdy.1992.145

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Keywords

  • chromosome loss
  • Drosophila lummei
  • Drosophila virilis
  • hybrid inviability
  • morphological anomalies
  • speciation
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