Table 4 Accuracy of mapping epistatic pair in the core scenariosa

From: Controlling false positives in the mapping of epistatic QTL

 

Exactb (%)

Locus 1 precision (cM) c

Locus 2 precision (cM) c

  

1D_path

2D_path

1D_path

2D_path

Com2.5%

10.1

3.0 (96.8, 3.2)

2.7 (100, 0.0)

3.4 (95.7, 4.3)

1.9 (100, 0.0)

Com5.0%

64.2

1.7 (100, 0.0)

1.8 (100, 0.0)

1.7 (99.8, 0.2)

1.7 (100, 0.0)

Com7.5%

96.6

1.3 (100, 0.0)

1.3 (100, 0.0)

1.3 (100, 0.0)

1.3 (100, 0.0)

Dup2.5%

1.5

5.1 (88.9, 11.1)

3.8 (100, 0.0)

4.3 (88.9, 11.1)

3.9 (100, 0.0)

Dup5.0%

15.8

4.2 (85.9, 14.1)

3.8 (93.3, 6.7)

4.9 (85.9, 12.9)

4.0 (89.6, 10.4)

Dup7.5%

41.9

4.8 (89.5, 9.8)

4.0 (92.8, 6.5)

4.7 (90.2, 9.0)

3.5 (94.1, 5.6)

Dom2.5%

3.3

4.3 (88.6, 11.4)

4.0 (87.5, 12.5)

8.8 (80.0, 14.3)

8.1 (75.0, 12.5)

Dom5.0%

35.1

2.8 (98.5, 1.5)

2.3 (98.3, 1.7)

4.6 (91.0, 7.1)

4.2 (93.4, 4.1)

Dom7.5%

66.7

1.7 (99.7, 0.3)

2.0 (99.4, 0.6)

3.5 (95.7, 4.1)

3.7 (94.9, 4.8)

Rec2.5%

4.6

6.4 (81.1, 18.9)

6.4 (88.9, 0.0)

3.2 (97.3, 2.7)

4.9 (77.8, 22.2)

Rec5.0%

32.4

5.2 (84.4, 14.1)

4.8 (86.5, 11.3)

1.9 (100, 0.0)

1.9 (110.0, 0.0)

Rec7.5%

62.9

4.4 (92.1, 6.0)

3.9 (94.4, 4.8)

1.7 (99.6, 0.4)

1.5 (99.7, 0.3)

Inh2.5%

7.3

2.7 (100, 0.0)

3.5 (100, 0.0)

5.2 (87.7, 12.3)

4.3 (100, 0.0)

Inh5.0%

39.8

2.2 (99.4, 0.6)

1.9 (100, 0.0)

4.4 (91.3, 7.0)

3.4 (96.6, 3.4)

Inh7.5%

72.3

1.6 (99.9, 0.1)

1.5 (100, 0.0)

3.4 (95.6, 4.0)

3.3 (96.3, 3.3)

Int2.5%

0.0

—

5.0 (100, 0.0)

—

8.1 (80.0, 20.0)

Int5.0%

6.7

—

4.9 (89.9, 10.1)

—

4.2 (91.3, 8.7)

Int7.5%

24.1

—

4.4 (91.1, 8.5)

—

4.3 (89.9, 10.1)

Int10.0%

45.3

—

3.9 (92.6, 7.1)

—

4.0 (93.1, 6.4)

Int12.5%

58.9

—

3.5 (95.5, 4.5)

—

3.6 (94.8, 4.9)

  1. aEach scenario with one non-epistatic QTL and one epistatic pair.
  2. bThe percentage of the number of true positive epistatic pairs in which both loci mapped to the simulated marker interval out of the total simulation replicates.
  3. cThe average distance between the mapped and simulated QTL positions for significant epistatic pairs given for each QTL separately; the first (second) number in brackets is the percentage of distances ⩽10 cM (>10 and ⩽20 cM) out of the total number of true positives.
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