Figure 1

Nucleotide mutations in the melanocortin receptor 1 (MC1R)-coding region defining 20 haplotypes and the haplotype distribution frequency. The codon and nucleotide positions are numbered from the first nucleotide of the start codon. Dots indicate that the identity of MC1R^*5. MC1R^*1, ^*2, ^*5 correspond to those reported previously (Kijas et al., 1998; Giuffra et al., 2000). MC1R^*3, ^*4, ^*6 were not found in this study. ^aMC1R^*25, ^b26–28, ^c29, ^d30 and ^e31 share the same haplotype in the coding region with MC1R^*1, 11, 12, 17 and 2, respectively.