Table 3 False positive rates obtained from the analysis of 10 independent sets of 1000 unlinked STR loci. in 53 populations replicating the sampling of the HGDP data set and generated under a scenario of a spatial expansion from Eastern Africa

From: Detecting loci under selection in a hierarchically structured population

Expected false positive rate

Balancing selection

Directional selection

 

Finite island

Hierarchical island

Finite island

Hierarchical island

  

10 groups

5 groups

 

10 groups

5 groups

0.001

0.010

0.002

0.002

0.042

0.006

0.005

0.005

0.045

0.010

0.010

0.083

0.014

0.014

0.01

0.080

0.027

0.027

0.110

0.021

0.026

0.05

0.219

0.130

0.130

0.138

0.089

0.091

  1. Abbreviation: HGDP, human genome diversity project.
  2. P-values were obtained from 50 000 simulations, in which the 53 populations were partitioned into five continental groups. Analyses under the finite island model were done by simulating a total of 100 demes. Under the hierarchical island model, we simulated either 5 or 10 groups of 100 demes.