Table 5 Human STR loci found significant at the 1% level of significance with closest known genes

Loci	P-value under the hierarchical island model	Pr(selection) ^a	Distance to closest gene (kb) ^b	Name of closest gene	PANTHER biological processes
Balancing selection
D3S2427	0.0002	1	261	NAALADL2	Unclassified^c
D4S3248	0.0081	0.62	378	AC096588.1	No match^d
D7S2204	0.0095	0.23	0	MAGI2	Cell communication, synaptic transmission
ATAG022_5	0.0025	×	77	SLC1A3	Amino-acid transport, ligand-mediated signalling, ion transport, synaptic transmission
D14S742	0.0094	1	3	AE000658.1	No match^d
AGAT139P_20	0.0018	×	0	MACROD2	Unclassified^c
Directional selection
D8S560	0.0085	1	0	GFRA2	Unclassified^c
D6S1006	0.0081	1	0	PHACTR1	Neuronal activities, cell structure
D9S1120	0.0098	×	69	AGTPBP1	Proteolysis, signal transduction
D2S1400	0.0006	×	1	E2F6	mRNA transcription regulation, signal transduction, developmental processes, cell-cycle control, cell proliferation and differentiation
MFD427-AAAT0	0.0081	1	0	IQCG	Unclassified^c
AATA045_4	0.0017	×	86	AC108142.1	No match^d
ATA31F09M_7	0.0070	0.63	139	INHBA	Other receptor mediated signalling pathway, developmental processes, cell proliferation and differentiation
ATAC026P_14	1.00E−07	1	0	C14orf143	Unclassified

^a Probability of a marker being under selection, as previously reported by Foll and Gaggiotti (2008) using a Bayesian approach under a non-hierarchical genetic structure. A cross indicates a marker that was not tested by these authors.
^b Distance from closest gene transcript, including any known gene.
^c Biological process is unclassified in the PANTHER (Thomas et al., 2003) data base.
^d This gene was not found in the PANTHER data base.

Quick links

Search