Figure 1
Estimates of the proportions of mutations in different −Nes ranges for simulated datasets with various purifying selection coefficients. (a) Under constant population size; (b) under a fivefold population expansion, starting in the past at time 0.8 (in units of 4N2 generations). Neutral mutations (black solid line with diamonds), −NeE(s)=5 (long dashed gray line with rectangles), −NeE(s)=50 (short dashed black line with triangles), −NeE(s)=500 (long dashed black line with crosses) and −NeE(s)=5000 (gray solid line with circles). Means±s.e. are shown for 50 independent simulated datasets for each selection coefficient (means sharing a letter are not significantly different at the 0.01 level according to a Tukey's honestly significantly different test). The demographic parameters are N2/N1=5 and t/4N2=0.8, and the shape of the γ distribution (DFE shape) b=0.1.
