Table 2 Results of power analyses for estimates of demographic and DFE parameters

From: Fitness effects of derived deleterious mutations in four closely related wild tomato species with spatial structure

−NeE(s)

Expansion

N 2 /N 1

RMSE (N2/N1)a

t/4N 2

RMSE (t/4N2)a

b

RMSE (b)

0 (Neutral)

None

4.37 (0.5)

—

4.37 (1.57)

—

8.39 (3.84)

28.42

 

Fivefold

4.97 (0.1)

3.57

1.76 (0.5)

3.71

17.93 (5.1)

3.71

5

None

6.63 (0.46)

—

0.8 (0.28)

—

20.68 (5.6)

44.72

 

Fivefold

7.08 (0.42)

3.6

0.77 (0.10)

0.73

17 (5.17)

0.73

50

None

6.9 (0.47)

—

1.29 (0.32)

—

17.4 (5.13)

40.18

 

Fivefold

5.95 (0.41)

3.07

0.53 (0.08)

0.67

6.06 (3.35)

0.67

500

None

7.03 (0.41)

—

0.5 (0.16)

—

7.89 (3.72)

27.43

 

Fivefold

7.6 (0.51)

4.47

1.3 (0.08)

0.73

0.13 (0.02)

0.73

5000

None

6.57 (0.46)

—

0.8 (0.26)

—

0.09 (0.01)

0.07

 

Fivefold

8.15 (0.45)

4.48

1.38 (0.1)

0.9

0.095 (0.008)

0.9

  1. Abbreviations: DFE, distribution of fitness effect; RMSE, root mean square error.
  2. Estimated parameters are the ratio of current and ancestral effective population size (N2/N1), the time of expansion (t/4N2), and the shape of the DFE γ distribution (b). Means of estimates (standard error) and RMSE were calculated using 50 independent simulated datasets with true parameter values: −NeE(s)=0, 5, 50, 500 and 5000, N2/N1=5, t/4N2=0.8 and b=0.1.
  3. aThe RMSE of the expansion factor or time of expansion was not calculated in simulations with constant population size.
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