Figure 1
From: Epigenetic regulation of development by histone lysine methylation
Profiles of histone lysine methylation at active and inactive mammalian genes. At active genes, H3K4me3 is highly enriched at the promoter region, whereas H3K36me3 associates with the gene body. At repressed genes, H3K27me3 covers the gene body and flanking regions. H3K9me3 and H4K20me3 are also enriched at inactive genes, although at a lower level (adapted from Barski et al., 2007, Pauler et al., 2009 and Cui et al., 2009).
