Table 1 Mammalian histone methylation binders and their possible functions

Histone modification	Reader	Function	Reference
H3K4
me2, me3	Chd1	Chromatin remodeling	Flanagan et al. (2005)
me3	Bptf	Chromatin remodeling	Wysocka et al. (2006)
me3	Taf3	TFIID stabilization	Vermeulen et al. (2007)
me3	Ing1	Recruitment of HATs	Taverna et al. (2006)
me3	Ing2	Recruitment of HDACs	Shi et al. (2006)
me3	Ing4	Recruitment of HATs	Hung et al. (2009)
me3	Ing5	Recruitment of HATs	Champagne et al. (2008)
me3	Jmjd2a	H3K9 demethylation	Lee et al. (2008b)
me3	Chd7	Chromatin remodeling	Takada et al. (2007)
me3	Rag2	VDJ recombination	Matthews et al. (2007)
H3K9
me1, me2	G9a-GLP	Transcriptional silencing	Collins et al. (2008)
me3	HP1	Heterochromatin	Lachner et al. (2001)
me3	Tip60	DNA repair	Sun et al. (2009)
me3	Chd7	Chromatin remodeling	Takada et al. (2007)
me3	Cdyl2	Heterochromatin	Fischle et al. (2008)
H3K27
me3	Cbx2,4,7	Polycomb-mediated gene silencing	Bernstein et al. (2006b)
me3	Eed	Polycomb-mediated gene silencing	Margueron et al. (2009)
H3K36
me3	Mrg15	Recruitment of HDACs	Zhang et al. (2006)
H3K79
me1, me2	53bp1	DNA damage repair	Huyen et al. (2004)
H4K20
me1, me2	L3mbtl1	Chromatin compaction	Trojer et al. (2007)
me2	53bp1	DNA damage repair	Botuyan et al. (2006)
me3	Jmjd2a	H3K9 demethylation	Lee et al. (2008b)

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