Table 5 The frequency of HLA class I antigen Bw53 typed in two independent samples (sample sizes in parentheses) of young children by either serotyping or PCR and class II haplotype DQw5 in a population from Gambia for individuals with severe malaria or mild controls (Hill et al., 1991)

From: Population genetics of malaria resistance in humans

 

Bw53 (class I)

DQw5 (class II)

 

Serotype

PCR

 

Severe malaria

0.157 (306)

0.169 (307)

0.057 (436)

Mild controls

0.243 (144)

0.254 (364)

0.105 (958)

 OR

0.580

0.597

0.515

 s

0.041

0.046

  1. Below are given the odds ratio (OR) and the selection coefficient (assuming m=0.1) for Bw53 and for DQw5.
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