Table 1 Nucleotide diversity and MLHKA test for the two analyzed SELP and SELPLG regions

From: An evolutionary history of the selectin gene cluster in humans

Gene region

Size (Kb)

Pop.

Na

Sb

θW ( × 10−4)

π ( × 10−4)

MLHKA

     

Value

Rank c

Value

Rankc c

kd

P-value

SELP ex9–10

6.6

AA

48

37

12.55

0.81

11.13

0.81

1.92

0.11

  

CEU

46

18

6.51

0.64

11.72

0.88

1.24

0.10

  

AS

40

15

4.97

0.42

1.55

0.07

1.04

0.13

SELP ex11–13

4.1

AA

48

52

28.88

>0.99

27.52

0.99

5.95

2.3 × 10−6

  

CEU

46

27

15.14

0.98

11.75

0.88

4.21

4.2 × 10−4

  

AS

40

15

8.69

0.87

6.12

0.63

2.83

0.012

SELPLG 5′

2.7

AA

48

18

15.06

0.91

10.54

0.79

2.46

0.062

  

CEU

46

13

10.99

0.90

9.64

0.83

2.57

0.064

  

AS

40

7

6.11

0.74

7.51

0.75

1.59

0.84

  1. Abbreviations: AA, African American; AS, Asian; CEU, Europeans; MLHKA, maximum-likelihood-ratio Hudson–Kreitman–Aguadé; Pop., population.
  2. aSample size (chromosomes).
  3. bNumber of segregating sites.
  4. cPercentile rank relative to a distribution of 5 kb windows from NIEHS genes.
  5. Selection parameter.
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