Figure 3
From: Population-specific recombination sites within the human MHC region
Recombination site within the sperm-typed recombination region between STR markers MOG-C to RF. (a) EHH plot of HLA-A haplotypes across the HLA-F telomeric recombination region (45 kb) previously defined by sperm typing. (b) The allelic calls of the Illumina GoldenGate MHC genotyped SNPs on the HLA-A*02:01 and HLA-A*02:07 haplotypes telomeric and centromeric of the recombination interval. (c) Resequencing across an 8 kb segment (position 29 790 868 to 29 798 998) that overlaps with the SNPs recombination interval. HLA-A*02:01 and HLA-A*02:07 haplotypes are derived from SNPs ascertained through resequencing. Positions highlighted in green correspond to SNPs in the Illumina GoldenGate MHC panel and their allelic calls are highlighted in red while the others are polymorphic sites revealed by resequencing. (d) Location of 660 bp recombination site refined by resequencing and the repetitive elements in close proximity to the site.
