Table 1 Gene Ontology (GO) analysis of the downregulated genes identified in the resistant Y chromosome males relative to SR1227

From: Natural variation of the Y chromosome suppresses sex ratio distortion and modulates testis-specific gene expression in Drosophila simulans

GO term

Biological process

P-value a

No. of genes

GO:0045333

Cellular respiration

1.34E−19

33

GO:0015980

Energy derivation by oxidation of organic compounds

2.91E−18

33

GO:0006091

Generation of precursor metabolites and energy

1.47E−16

35

GO:0022904

Respiratory electron transport chain

8.97E−16

25

GO:0022900

Electron transport chain

5.69E−15

25

GO:0042773

ATP synthesis coupled electron transport

5.79E−13

22

GO:0042775

Mitochondrial ATP synthesis coupled electron transport

2.11E−12

21

GO:0006119

Oxidative phosphorylation

4.40E−12

22

GO:0006120

Mitochondrial electron transport, NADH to ubiquinone

6.54E−08

13

GO:0007602

Phototransduction

6.04E−07

14

GO:0009583

Detection of light stimulus

0.0000028

14

GO:0055114

Oxidation–reduction process

0.0000149

47

GO:0009581

Detection of external stimulus

0.0000454

14

GO:0009060

Aerobic respiration

0.0028969

10

GO:0009416

Response to light stimulus

0.0078173

15

GO:0009314

Response to radiation

0.0089795

16

GO:0006084

Acetyl-CoA metabolic process

0.0341105

9

  1. Abbreviations: ATP, adenosine triphosphate; NADH, nicotinamide adenine dinucleotide.
  2. aCorrected with the Holm–Bonferroni Multiple Hypothesis Test.