Table 1 Rare founder mutations prevalent in tribes participating in our LAB data set

From: Deciphering the fine-structure of tribal admixture in the Bedouin population using genomic data

Disorder

OMIM

Tribes/clans

HRD—hypoparathyroidism retardation dysmorphism (Parvari et al. 2002)

241410

Clan A

CIPA—congenital insensitivity to pain (Parvari et al., 2002)

256800

Clan A

Complex 3—mitochondrial complex III deficiency (Barel et al., 2008)

124000

Clan B

PHHI—persistent hyperinsulinemic hypoglycemia of infancy (Glaser et al., 1990)

256450

Clan B

Deafness—nonsyndromic autosomal recessive deafness (Scott et al., 1995)

220290

Clan B, tribe M

LCCS 2—lethal congenital contracture syndrome (Narkis et al., 2004)

607598

Tribes L, M

LCCS 4—lethal congenital contracture syndrome (Markus et al., 2012)

614915

Tribes N, O

Bartter syndrome (Finer et al., 2003)

241200

Tribe P and a single carrier from tribe Q

  1. This table presents disorders with specific founder mutations prevalent in certain tribes and clans. Clan-specific mutations distinguish clan A, one of the oldest Negev clans, from the rest of the tribes, consistent with the oral history described in the main text.
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