Figure 2

P-values for parasite relatedness (R) and multilocus heterozygosity (MLH) after 1000 randomizations. Each bar represents an individual human host (labeled according to the numbering in Table 1) or the pool of cercariae from the village Ndieumeul (named ‘Cercariae’). Vertical lines were drawn for P=0.05; values smaller than this line are considered significant. Robs>Rexp reflects the probability of observing higher pairwise relatedness than expected, suggesting biased sampling of (many) siblings from a limited number of adults for this host. Only host 46 was highly significant for this test. MLHobs<MLHexp reflects the probability of observing a lower individual heterozygosity than expected from random mating, suggesting parasite inbreeding. This test was significant for 33 human hosts. See Supplementary Table S2 for exact P-values.