Table 2 Lethal concentrations (CL, μm) of CAP18(FV) and its mutants against Gram-positive bacteria
CAP18(FV) | CAP18(FV)(2-31) | CAP18(FV)-HsNC | CAP18(FV)-TtNC | |
|---|---|---|---|---|
BC CGMCC 1.1846 | NA | NA | NA | NA |
BM CGMCC 1.0459 | 1.40 | 1.46 | 1.64 | 1.92 |
BS CGMCC 1.2428 | 1.10 | 1.45 | 1.80 | 2.36 |
ML CGMCC 1.0290 | 0.94 | 0.90 | 1.18 | 1.50 |
SA CGMCC 1.89 | NA | NA | NA | NA |
SA (J685,J698,J700 J706,J708,J710) | NA | NA | NA | NA |
PSSE P1111 | NA | NA | NA | NA |
MRCNS P1369 | 1.57 | 1.44 | 1.48 | 2.09 |
MRSA P1374 | 1.20 | 1.46 | 2.08 | 2.13 |
MRSA P1381 | 1.73 | 1.46 | 1.85 | 2.17 |
PRSA P1383 | 1.19 | 1.35 | 1.74 | 2.29 |
PRSE P1386 | NA | NA | NA | NA |
PRSE P1389 | 1.00 | 1.15 | 1.30 | 1.87 |
SW ATCC 1.2824 | 1.38 | 0.78 | 1.00 | 2.17 |
SG NBRC 13350 | 6.36 | 8.84 | 5.68 | ND |
SSCA CGMCC 4.1765 | 1.84 | 3.10 | 8.93 | 8.66 |
SM ATCC 1.2499 | 1.67 | 0.73 | 2.02 | 4.97 |
SSAL ATCC 1.2498 | 2.25 | 2.66 | 2.79 | 4.13 |
SSAN ATCC 1.2497 | 1.16 | 1.75 | 2.81 | 3.83 |
