Figure 1
Alignments of amino acid sequences of MHC class I exon 3 (a) and MHC class II exon 2 (b) of Centrocercus and Tympanuchus grouse; subsets containing 15 representative alleles are shown for each MHC class. MHC class II alleles not found at BLB1 locus are in frames. Dots indicate the same amino acid with top sequence. Grey shading indicates putative ABS according to Kaufman et al. (1992) for MHC class I and according to Brown et al. (1993) and/or Bondinas et al. (2007) for MHC class II. Amino acid residues under positive selection are marked with a plus (+), under negative selection are marked with a dash (−) and under episodic diversifying selection are marked with an asterisk (*). Spatial variation in the selection parameter (normalized dN—dS) is shown at the top of each alignment.
