Figure 3
Regional association plot for imputed single-nucleotide polymorphism–alkaline phosphatase associations in the regions around and within the FUT1 and FUT2 loci. The P values of the imputed genotypes of the single-nucleotide polymorphisms in association analysis with serum alkaline phosphatase levels are plotted (as −log10 values) against their physical locations on chromosome 19. The estimated recombination rates in the Asian population of the 1000 Genomes Project (March 2012 release) show the local linkage disequilibrium structure. Each significant single-nucleotide polymorphism (P value<5×10−8) is indicated by an arrow. Inset: colors of other single-nucleotide polymorphisms indicate linkage disequilibrium with rs2071699 according to a scale from r2=0 to 1 based on pairwise r2 values from 1000 Genomes Project.
