Figure 1
From: p.G970D is the most frequent CFTR mutation in Chinese patients with cystic fibrosis
CFTR mutation spectrum in Chinese patients with CF. Upper panel: CFTR mutations identified in our current (eight CFs) and previous (seven CFs) (#14–20, as in Table 2) samples of Chinese CF patients collected at PUMCH. The three novel mutations identified in the current study are highlighted in green; the most common mutation found in Chinese CF patients thus far is highlighted in blue; the most common mutation found in Caucasian CF patients is highlighted in purple. Lower panel: CFTR mutations identified in previous studies (#1–13 as in Table 2) in Chinese patients with CF. The CFTR gene is shown with rescaled exons and minimized introns, and is not drawn to scale. CF, cystic fibrosis; PUMCH, Peking Union Medical College Hospital.
