Figure 1

Sanger sequences of the patient and parents in BBS10 and predicted amino acid sequences. (a) The patient and mother have NM_024685.3:c.1677C>A mutation (arrow), which causes the termination of the BBS10 protein. (b) The patient and father have NM_024685.3:c.1974T>G mutation (arrow), which causes the termination of the protein. Thus, the patient has compound heterozygous mutations in the BBS10 gene.