Table 1 Demographic and profile statistics of iMETHYL

From: iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation

 

Monocytes

CD4+ T cells

Neutrophils

Demographic characteristics of subjects

 N

102a

102a

94

 Males, N (%)

48 (47.1)

49 (48.0)

48 (51.1)

 Median age (range), years

62.5 (35–75)

62.0 (35–75)

58.0 (24–81)

DNAm profiles

 Sequencing depthb

31.1±1.8

31.0±1.6

54.7±1.6

 No. of autosomal CpGsc

23 ,941,821

24,037,518

25,483,031

Gene expression profiles

 No. of sequencing readsb

33,917,157±3,153,528

35,175,996±1,275,575

47,040,140±6,289,540

 No. of genesd

16,282

18,299

14,534

SNV profiles

 Sequencing depthb

27.2±1.0

27.2±1.0

53.3±13.2

 No. of SNVse

8,945,669

8,951,822

8,792,880

  1. Abbreviations: DNAm, DNA methylation; SNV, single-nucleotide variant.
  2. a Both cell types were obtained from the same 95 individuals out of a cohort of 102.
  3. b Average±standard deviation.
  4. c CpGs that were retained in ≥50% of subjects for each cell type.
  5. d Genes that were expressed with a fragments per kilobase of exon per million mapped fragments ≥0.1 in ≥50% of subjects for each cell type.
  6. e SNVs with a minor allele count >1.
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