Article PDF
References
Masdeu JC, Wolfson L, Lantos G, et al: Brain white-matter changes in the elderly prone to falling. Arch Neurol 1989; 46: 1292–1296.
Vermeer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ, Breteler MM : Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med 2003; 348: 1215–1222.
Kobayashi S, Okada K, Koide H, Bokura H, Yamaguchi S : Subcortical silent brain infarction as a risk factor for clinical stroke. Stroke 1997; 28: 1932–1939.
Kario K, Pickering TG, Matsuo T, Hoshide S, Schwartz JE, Shimada K : Stroke prognosis and abnormal nocturnal blood pressure falls in older hypertensives. Hypertension 2001; 38: 852–857.
Shimada K, Kawamoto A, Matsubayashi K, Nishinaga M, Kimura S, Ozawa T : Diurnal blood pressure variations and silent cerebrovascular damage in elderly patients with hypertension. J Hypertens 1992; 10: 875–878.
Kario K, Matsuo T, Kobayashi H, Imiya M, Matsuo M, Shimada K : Nocturnal fall of blood pressure and silent cerebrovascular damage in elderly hypertensive patients. Advanced silent cerebrovascular damage in extreme dippers. Hypertension 1996; 27: 130–135.
Kario K, Matsuo T, Kobayashi H, Asada R, Matsuo M : 'Silent' cerebral infarction is associated with hypercoagulability, endothelial cell damage, and high Lp(a) levels in elderly Japanese. Arterioscler Thromb Vasc Biol 1996; 16: 734–741.
Kario K, Matsuo T, Kobayashi H, Hoshide S, Shimada K : Hyperinsulinemia and hemostatic abnormalities are associated with silent lacunar cerebral infarcts in elderly hypertensive subjects. J Am Coll Cardiol 2001; 37: 871–877.
Eguchi K, Kario K, Shimada K : Greater impact of coexistence of hypertension and diabetes on silent cerebral infarcts. Stroke 2003; 34: 2471–2474.
Eguchi K, Kario K, Hoshide S, et al: Greater change of orthostatic blood pressure is related to silent cerebral infarct and cardiac overload in hypertensive subjects. Hypertens Res 2004; 27: 235–241.
Eguchi K, Kario K, Hoshide S, et al: Smoking is associated with silent cerebrovascular disease in a high-risk Japanese community-dwelling population. Hypertens Res 2004; 27: 747–754.
Hasegawa Y, Yamaguchi T, Omae T, Woodward M, Chalmers J : Effects of perindopril-based blood pressure lowering and of patient characteristics on the progression of silent brain infarct: the Perindopril Protection against Recurrent Stroke Study (PROGRESS) CT Substudy in Japan. Hypertens Res 2004; 27: 147–156.
Kato T, Inoue T, Yamagishi S, Morooka T, Okimoto T, Node K : Low-density lipoprotein subfractions and the prevalence of silent lacunar infarction in subjects with essential hypertension. Hypertens Res 2006; 29: 303–307.
Hoshide S, Kario K, Mitsuhashi T, et al: Different patterns of silent cerebral infarct in patients with coronary artery disease or hypertension. Am J Hypertens 2001; 14: 509–515.
Uehara T, Tabuchi M, Mori E : Risk factors for silent cerebral infarcts in subcortical white matter and basal ganglia. Stroke 1999; 30: 378–382.
Cromwell WC, Otvos JD : Low-density lipoprotein particle number and risk for cardiovascular disease. Curr Atheroscler Rep 2004; 6: 381–387.
Ross R : The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801–809.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hoshide, S., Kario, K. Low-Density Lipoprotein Subfraction as a New Risk Factor for Silent Cerebral Infarction in Hypertensive Patients. Hypertens Res 29, 297–298 (2006). https://doi.org/10.1291/hypres.29.297
Received:
Issue date:
DOI: https://doi.org/10.1291/hypres.29.297
