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Hypertension Research
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Independent Determinants of Second Derivative of the Finger Photoplethysmogram among Various Cardiovascular Risk Factors in Middle-Aged Men
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  • Original Article
  • Published: 01 December 2007

Independent Determinants of Second Derivative of the Finger Photoplethysmogram among Various Cardiovascular Risk Factors in Middle-Aged Men

  • Toshiaki Otsuka1,
  • Tomoyuki Kawada1,
  • Masao Katsumata1,
  • Chikao Ibuki2 &
  • …
  • Yoshiki Kusama3 

Hypertension Research volume 30, pages 1211–1218 (2007)Cite this article

  • 1738 Accesses

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Abstract

The second derivative of the finger photoplethysmogram (SDPTG) has been used as a non-invasive examination for arterial stiffness. The present study sought to elucidate independent determinants of the SDPTG among various cardiovascular risk factors in middle-aged Japanese men. The SDPTG was obtained from the cuticle of the left-hand forefinger in 973 male workers (mean age: 44±6 years) during a medical checkup at a company. The SDPTG indices (b/a and d/a) were calculated from the height of the wave components. Multiple logistic regression analyses revealed that the independent determinants of an increased b/a (highest quartile of the b/a) were age (odds ratio [OR]: 1.12 per 1-year increase, 95% confidence interval [CI]: 1.09–1.15), hypertension (OR: 1.65, 95% CI: 1.03–2.65), dyslipidemia (OR: 1.51, 95% CI: 1.09–2.09), impaired fasting glucose/diabetes mellitus (OR: 2.43, 95% CI: 1.16–5.07), and a lack of regular exercise (OR: 2.00, 95% CI: 1.29–3.08). Similarly, independent determinants of a decreased d/a (lowest quartile of the d/a) were age (OR: 1.11 per 1-year increase, 95% CI: 1.08–1.14), hypertension (OR: 3.44, 95% CI: 2.20–5.38), and alcohol intake 6 or 7 days per week (OR: 2.70, 95% CI: 1.80–4.06). No independent association was observed between the SDPTG indices and blood leukocyte count or serum C-reactive protein levels. In conclusion, the SDPTG indices reflect arterial properties affected by several cardiovascular risk factors in middle-aged Japanese men. The association between inflammation and the SDPTG should be evaluated in further studies.

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Author information

Authors and Affiliations

  1. Environmental Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan

    Toshiaki Otsuka, Tomoyuki Kawada & Masao Katsumata

  2. Cardiovascular Center, Nippon Medical School Chiba-Hokusoh Hospital, Chiba, Japan

    Chikao Ibuki

  3. Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan

    Yoshiki Kusama

Authors
  1. Toshiaki Otsuka
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  2. Tomoyuki Kawada
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  3. Masao Katsumata
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  4. Chikao Ibuki
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  5. Yoshiki Kusama
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Corresponding author

Correspondence to Toshiaki Otsuka.

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Cite this article

Otsuka, T., Kawada, T., Katsumata, M. et al. Independent Determinants of Second Derivative of the Finger Photoplethysmogram among Various Cardiovascular Risk Factors in Middle-Aged Men. Hypertens Res 30, 1211–1218 (2007). https://doi.org/10.1291/hypres.30.1211

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  • Received: 08 June 2007

  • Accepted: 25 July 2007

  • Issue date: 01 December 2007

  • DOI: https://doi.org/10.1291/hypres.30.1211

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Keywords

  • arterial stiffness
  • cardiovascular preventive medicine
  • finger photoplethysmogram
  • risk factors

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