Figure 4

Blood pressure response rates during long-term aliskiren-based therapy. BP response: mean sitting diastolic blood pressure <90 and/or ⩾10 mm Hg decrease from the pretreatment baseline. End point is week 52 or last observation carried forward. Week 4: aliskiren 75 or 150 mg monotherapy. Week 8: aliskiren 75, 150, or 300 mg monotherapy. *Week 16 to the end point: aliskiren 75, 150, or 300 mg monotherapy and combination therapy with a diuretic or calcium channel blocker.