Table 1 Clinical characteristics of study subjects with microbleeds
From: Silent cerebral microbleeds associated with arterial stiffness in an apparently healthy subject
Microbleeds | ||
|---|---|---|
Present (n=22) | Absent (n=421) | |
Sex (male/female) | 7/15 | 154/268 |
Age (years) | 72.2±5.9** | 66.8±8.1 |
Body mass index (kg m−2) | 23.3±3.8 | 23.0±3.0 |
Systolic blood pressure (mm Hg) | 146±23 | 139±19 |
Diastolic blood pressure (mm Hg) | 81±13 | 78±11 |
Pulse pressure (mm Hg) | 65±17 | 60±14 |
LDL cholesterol (mg dl−1) | 123±27 | 128±33 |
HDL cholesterol (mg dl−1) | 68±22 | 68±19 |
Triglyceride (mg dl−1) | 94±45 | 106±59 |
Glucose (mg dl−1) | 105±16 | 103±19 |
HbA1c (%) | 5.6±0.5 | 5.6±0.7 |
Immunoreactive insulin (μU ml−1) | 6.1±3.2 | 5.9±4.7 |
HOMA-IR | 1.6±1.0 | 1.6±2.0 |
Current smokers (%) | 0 | 6.2 |
Hypertension (%) | 90.9** | 54.9 |
Type 2 diabetes (%) | 18.2 | 10.2 |
History of atrial fibrillation (%) | 4.5 | 0.5 |
LVH on electrocardiogram (%) | 4.5 | 11.1 |
Antihypertensive drugs (%) | 50.0** | 23.8 |
Antidiabetic drugs (%) | 9.1 | 5.2 |
Antiplatelet drugs (%) | 4.5 | 4.0 |
Framingham stroke risk score (%) | 12.1±8.6* | 8.9±7.5 |
baPWV (cm s−1) | 1820±308* | 1645±325 |
Carotid IMT (mm) | 0.85±0.14 | 0.81±0.15 |
Diameter at end diastole (mm) | 6.6±0.7* | 6.3±0.8 |
Diameter at peak systole (mm) | 7.1±0.8* | 6.7±0.8 |
Number of plaques | 1.09±1.34 | 0.78±1.17 |
