Table 3 Regression analysis for changes in SAA–LDL and CAVI during treatment with EPA

From: Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome

 

ΔSAA–LDL

ΔCAVI

 

Univariate

Multivariate

Univariate

Multivariate

ΔBW

0.191

−0.083

ΔBMI (kg m−2)

0.255

−0.025

ΔWaist circumference

0.090

0.004

ΔSystolic blood pressure

−0.137

0.218

ΔDiastolic blood pressure

−0.110

0.066

ΔFasting plasma glucose

0.147

0.101

ΔHbA1c

−0.066

−0.068

ΔIRI

−0.044

−0.037

ΔTotal cholesterol

0.360*

0.293*

0.278

ΔLDL-C

−0.005

−0.075

ΔHDL-C

0.081

−0.141

ΔTriglyceride

0.287

0.160

ΔSAA–LDL

  

0.381*

0.381*

ΔLeptin

0.003

0.211

ΔAdiponectin

−0.331*

−0.305*

−0.213

ΔCRP

0.365*

0.158

ΔPWV

0.366*

  

ΔCAVI

0.381*

0.325*

  
  1. Abbreviations: BMI, body mass index; CAVI, cardio-ankle vascular index; CRP, high-sensitive C-reactive protein; EPA, eicosapentaenoic acid; HbA1c, hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; IRI, immunoreactive insulin; LDL-C, low-density lipoprotein cholesterol; PWV, pulse wave velocity; SAA–LDL, serum amyloid A–LDL.
  2. Multivariate regression analysis was performed with adjustments for all metabolic parameters as independent variables.
  3. *P<0.05.