Table 2 Clinical characteristics of study subjects with MCI

From: Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly: the J-SHIPP study

 

Mild cognitive impairment (n=38)

Normal cognitive function (n=106)

P-value

Age (years)

74±6

67±6

<0.001

Sex (male/female)

17/21

32/74

0.104

Body mass index (kg/m2)

23±3

23±3

0.818

Hypnotic treatment

5

4

0.040

Type II diabetes (n)

7

9

0.095

Brachial-ankle pulse wave velocity (cm s−1)

1808±380

1595±285

0.001

Systolic BP

 Clinic (mm Hg)

139±19

136±20

0.358

 24-h (mm Hg)

135±15

128±14

0.019

 Awake (mm Hg)

138±14

131±15

0.020

 Sleeping (mm Hg)

125±23

116±15

0.008

 Nocturnal BP change (%)

−10±12

−12±8

0.291

Diastolic BP

   

 Clinic (mm Hg)

76±11

77±10

0.537

 24-h (mm Hg)

76±6

77±7

0.888

 Awake (mm Hg)

78±6

79±7

0.774

 Sleeping (mm Hg)

70±10

68±8

0.193

 Nocturnal BP change (%)

−10±12

−13±9

0.127

Apolipoprotein E ɛ4 allele (n)

14

20

0.025

  1. Abbreviation: BP, blood pressure.
  2. Values are mean±s.d. Mild cognitive impairment was assessed by MCI screen.12 Ambulatory blood pressure was measured in 15-min intervals during the day (0700 to 2000 hours) and at 30-min intervals at night. Type II diabetes was diagnosed as either or both fasting blood glucose ⩾126 mg per 100 ml or the current use of oral antidiabetic agents.
Back to article page