Table 1 Direct comparison of the efficacies of ARBs in clinical trials

From: Do angiotensin II type 1 receptor blockers have molecular effects?

Effects

Efficacies

Reducing left ventricular mass18

Val>Los

Lowering plasma PAI-1 and MCP-119

Can>Los

Preventing coronary artery contraction20

Ex>Can

Preventing coronary restenosis21

Val>Los

Reducing CRP22

Olm>Val

Reducing plasma Ad and Glu23

Tel>Can

Inhibiting platelet activation24

Los>Val

Reducing IL-6 and CRP25

Olm>Tel

Improving Glu and lipid profiles26

Tel>Olm

  1. Abbreviations: Ad, adiponectin; Angiotensin II type 1 receptor blocker; Can, candesartan; CRP, C-reactive protein; Ex, Exp3174; Glu, glucose; IL-6, interleukin-6; Los, losartan; MCP-1, monocyte chemoattractant protein-1; Olm, olmesartan; PAI-1, plasminogen activator-inhibitor type-1 antigen; Tel, telmisartan; Val, valsartan.
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