Table 1 Baseline patient characteristics
Parameter | Control group (n=24) | Nephrotic syndrome group (n=21) | P |
---|---|---|---|
Age (years) | 54.3±18.2 | 58.5±14.8 | 0.407 |
Men/women | 11/13 | 8/13 | 0.600 |
Weight (kg) | 54.6±7.0 | 58.4±8.9 | 0.119 |
BMI (kg m−2) | 22.1±2.4 | 23.6±2.5 | 0.057 |
Body surface area (m2) | 1.53±0.13 | 1.58±0.16 | 0.302 |
Serum albumin (g per 100 ml) | 4.3±0.4 | 2.1±0.6 | <0.001 |
Serum creatinine (mg per 100 ml) | 0.81±0.20 | 0.85±0.26 | 0.572 |
Estimated glomerular filtration rate | |||
(ml min−1 1.73 m−2) | 66.9±14.7 | 64.4±24.9 | 0.680 |
24-h urinary protein excretion (g day−1) | ND | 5.5±1.8 | |
24-h urinary creatinine excretion (mg day−1) | ND | 890±382 (574–1374) | |
Creatinine clearance (ml min−1 1.73 m−2) | ND | 81.9±26.6 | |
24-h urinary sodium excretion (mmol day−1) | ND | 72±44 (64–216) | |
Histologic diagnosis | |||
Membranous nephropathy | 12 | ||
IgA nephropathy | 3 | ||
Minor glomerular abnormalities | 1 | ||
Membranoproliferative glomerulonephritis | 1 | ||
Lupus nephritis | 1 | ||
Amyloidosis | 2 | ||
Unknown | 1 |