Table 1 The 22 gene polymorphisms examined in this study
Locus | Gene | Symbol | Polymorphism | dbSNP |
|---|---|---|---|---|
1p31 | Leptin receptor | LEPR | G → A (Arg109Lys) | rs1137100 |
1q22 | Farnesyl diphosphate synthase | FDPS | A → C | rs2297480 |
1q32 | Complement factor H | CFH | T → C (Tyr402His) | rs1061170 |
3q27 | Alpha-2-HS-glycoprotein | AHSG | C → A (Thr270Thr) | rs1071592 |
6p21.3 | Advanced glycosylation end product-specific receptor | AGER | G → A (Gly82Ser) | rs2070600 |
6q27 | Thrombospondin 2 | THBS2 | 3949T → G (3′-UTR) | rs8089 |
7p15.3–p15.1 | Glucokinase | GCK | −30G → A | rs1799884 |
8q24.1–q24.3 | WNT1-inducible signaling pathway protein 1 | WISP1 | 2364A → G | rs2929970 |
10q23.3–q24.1 | Sorbin and SH3 domain-containing 1 | SORBS1 | 682A → G (Thr228Ala) | rs2281939 |
11p15.1 | ATP-binding cassette, subfamily C, member 8 | ABCC8 | −3C → T | rs1799854 |
11p15.1 | ATP-binding cassette, subfamily C, member 8 | ABCC8 | T → G (Ser1369Ala) | rs757110 |
11q13.1 | Actinin, alpha 3 | ACTN3 | C → T (Arg577Stop) | rs1815739 |
11q13.4 | Low-density lipoprotein receptor-related protein 5 | LRP5 | 4037T → C (Val1330Ala) | rs3736228 |
12q13.11 | Vitamin D receptor | VDR | 23005G → A | rs11568820 |
13q34 | Coagulation factor VII | F7 | 11496G → A (Arg353Gln) | rs6046 |
14q24.2–q24.3 | Deiodinase, iodothyronine, type II | DIO2 | C → T | rs12885300 |
15q24.1 | Cytochrome P450, family 1, subfamily A, polypeptide 2 | CYP1A2 | −163A → C | rs762551 |
16q12.2 | Solute carrier family 6, member 2 | SLC6A2 | 1287A → G (Thr429Thr) | rs5569 |
17p11.1 | A kinase anchor protein 10 | AKAP10 | 2073A → G (Ile646Val) | rs203462 |
17q11.2–q12 | Chemokine (C-C motif) ligand 2 | CCL2 | −2518C → T | rs1024611 |
20q13.1–q13.2 | Protein tyrosine phosphatase, non-receptor type 1 | PTPN1 | C → T | rs718049 |
22q11.23 | Glutathione S-transferase theta 1 | GSTT1 | I/D (3′-UTR) | Not detected |
