Table 2 Correlations between the expression of ABCA1, ABCG1, SR-BI, and plasma lipids, oxidized LDL and mean blood pressure in each separate group

From: The expression of ATP-binding cassette transporters in hypertensive patients

    

Hypertensive patients

 

Healthy control

Before therapy

After therapy

 

ABCA1

ABCG1

SR-BI

ABCA1

ABCG1

SR-BI

ABCA1

ABCG1

SR-BI

Mean blood pressure

0.31

0.36 *

0.15

0.32 *

0.30

0.18

0.31

0.37 *

0.19

Total cholesterol

0.11

0.10

0.11

0.25

0.22

0.06

−0.17

0.05

0.06

LDL cholesterol

0.04

0.08

0.03

−0.25

−0.03

0.13

0.04

0.11

0.09

HDL cholesterol

−0.04

−0.26

−0.23

−0.14

−0.11

−0.14

0.02

−0.18

−0.15

Triglyceride

0.22

−0.19

0.18

−0.11

−0.20

−0.04

0.22

0.11

0.08

Oxidized LDL

−0.03

−0.26

−0.27

−0.15

0.24

−0.11

−0.01

−0.26

−0.28

  1. Abbreviations: ABCA1, adenosine triphosphate-binding cassette transporter A1; ABCG1, adenosine triphosphate-binding cassette transporter G1; HDL, high-density lipoprotein, LDL, low-density lipoprotein; SR-BI, scavenger receptor class B type I.
  2. Pearson's correlation coefficients are shown. *P<0.05. ABCG1, ABCA1 and SR-BI mRNA were negatively transformed logarithmically before analysis. The values shown in bold indicate significant correlations were obtained in all the subjects combining healthy controls and untreated hypertensive patients.
Back to article page