Table 3 Correlation of clinical factors with UACR on multiple regression analysis

Variable	Partial regression coefficient	Standard partial regression coefficient	P-value	95 % CI
Model-1
BNP (pg ml⁻¹)	0.004	0.145	0.012	0.001–0.008
HbA1c (%)	0.347	0.198	0.001	0.139–0.555
TG (mg per 100 ml)	0.001	0.079	0.195	−0.001–0.004
TCHO (mg per 100 ml)	0.006	0.120	0.054	0.000–0.012
DMR	0.571	0.149	0.012	0.129–1.013
mSBP (mm Hg)	0.027	0.283	<.0001	0.016–0.038
Estimated duration of diabetes (years)	0.036	0.134	0.023	0.005–0.067
Sex	−0.410	−0.113	0.053	−0.827–0.006
Model-2
BNP (pg ml⁻¹)	0.005	0.166	0.007	0.001–0.008
HbA1c (%)	0.324	0.185	0.004	0.104–0.544
TG (mg per 100 ml)	0.002	0.104	0.105	0.000–0.004
TCHO (mg per 100 ml)	0.005	0.104	0.109	0.000–0.004
DMR	0.572	0.151	0.019	0.097–1.047
oSBP (mm Hg)	0.014	0.126	0.056	0.000–0.028
baPWV	0.001	0.146	0.022	0.000–0.001
Estimated duration of diabetes (years)	0.051	0.191	0.003	0.018–0.084
Sex	−0.433	−0.119	0.056	−0.877–0.011

Abbreviations: baPWV, brachial-ankle pulse wave velocity; BNP, brain natriuretic peptide; CI, confidence interval; DMR, diabetic retinopathy; TG, triglyceride; TCHO, total cholesterol.
Model 1 examined the association between UACR (objective variable:logarithmic transformation) and 13 variables, baseline hsCRP, BNP, HbA1c, TG, TCHO, DMR, morning SHBP, morning DHBP, baPWV, sex, age, estimated duration of hypertension, and estimated duration of diabetes (explanatory variables). In model 2, correlation with UACR (logarithmic transformation) was assessed using office SBP and office DBP instead of morning SHBP and morning DHBP.

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