Table 2 Simple linear regression analysis for determinants of MMSE score

From: High plasma aldosterone concentration is a novel risk factor of cognitive impairment in patients with hypertension

Variables

Coefficient

P-value

Age

−0.50

<0.01

Male

−0.14

0.26

Systolic blood pressure

−0.02

0.84

Diastolic blood pressure

−0.02

0.85

Mean blood pressure

−0.03

0.80

Pulse pressure

−0.04

0.76

PAC

−0.51

<0.01

PRA

0.22

0.09

LDL cholesterol

−0.25

<0.05

HDL cholesterol

0.11

0.38

Triglyceride

0.07

0.56

Hemoglobin A1c

−0.39

<0.01

Body mass index

0.01

0.94

eGFR

<0.01

0.99

Urinary albumin excretion

−0.08

0.52

Maximum plaque thickness

−0.01

0.92

Mean CCA blood flow volume

0.23

0.07

hs-CRP

−0.02

0.89

Urinary excretion of NOx

0.16

0.19

Urinary excretion of 8-OHdG

−0.12

0.34

Cerebral infarction

−0.32

<0.01

Hyperlipidemia

0.03

0.82

Diabetes mellitus

0.09

0.45

Current smoking

−0.17

0.17

  1. Abbreviations: CCA, common carotid artery; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; MMSE, mini-mental state examination; NOx, nitrate and nitrite; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; PAC, plasma aldosterone concentration; PRA, plasma renin activity.
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