Table 1 Body weight, heart weight and ratio of heart weight to body weight

From: Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats

  

SHR-SP

Parameters

WKY rats (n=6)

Placebo (n=6)

Candesartan (n=6)

Candesartan +amlodipine (n=6)

Candesartan +HCTZ (n=6)

Body weight (g)

257±4.5**

207±4.1

208±3.8

204±2.7

198±2.5

Heart weight (mg)

775±23

833±35

790±19

742±18**

717±23**,#

Heart weight/body weight (mg g−1)

3.02±0.11**

4.01±0.11

3.79±0.08

3.63±0.06**

3.62±0.09**

  1. Abbreviations: HCTZ, hydrochlorothiazide; SHR-SP, stroke-prone spontaneously hypertensive rats; WKY, Wistar-Kyoto.
  2. Values are mean±s.e.m. **P<0.01 vs. placebo. #P<0.05 vs. candesartan.
Back to article page