Table 1 Population characteristics

From: Association of (pro)renin receptor gene polymorphisms with lacunar infarction and left ventricular hypertrophy in Japanese women: the Ohasama study

 

Total

Men

Women

P-valuea

Number of subjects

779

250

529

 

Age, years

65.7±5.6

66.1±5.4

65.5±5.6

0.2

Body mass index, kg m–2

23.8±3.0

23.5±2.8

23.9±3.1

0.1

Current smoker, %

14.1

40.8

1.5

<0.0001

Current drinker, %

27.2

65.6

9.1

<0.0001

Diabetes mellitus, %

13.9

17.2

12.3

0.07

Hypertension, %

55.6

61.6

52.7

0.02

Antihypertensive medication, %

40.3

43.2

38.9

0.3

Hypercholesterolemia, %

18.2

8.0

23.1

<0.0001

Cardiac and cerebral disorders b

 Lacunar infarction, %

29.1

37.2

25.2

0.0007

 White matter hyperintensity, %

42.7

43.6

42.3

0.7

 Left ventricular hypertrophy, %

14.7

17.3

13.5

0.2

Ambulatory blood pressure

 24-h systolic, mm Hg

126.0±12.7

128.0±12.1

125.1±12.9

0.003

 24-h diastolic, mm Hg

73.2±7.3

75.2±6.6

72.3±7.5

<0.0001

 Daytime systolic, mm Hg

131.9±13.7

133.5±13.1

131.2±13.9

0.03

 Daytime diastolic, mm Hg

77.5±8.1

79.2±7.4

76.7±8.3

<0.0001

 Nighttime systolic, mm Hg

114.5±14.0

117.7±13.3

113.0±14.1

<0.0001

 Nighttime diastolic, mm Hg

65.0±7.6

67.7±7.2

63.8±7.5

<0.0001

Casual blood pressure

 Systolic, mm Hg

141.9±20.0

142.6±19.2

141.6±20.3

0.5

 Diastolic, mm Hg

78.4±10.4

79.5±10.9

77.9±10.2

0.06

Serum creatinine, mg dl–1

0.82±0.18

0.92±0.22

0.78±0.13

<0.0001

Plasma renin activityc, ng ml–1 h–1

1.0 (0.5–1.7)

1.3 (0.7–2.4)

0.9 (0.5–1.5)

<0.0001

  1. aMen vs. women.
  2. bNumber of cardiac and cerebral disorders: 738, lacunar infarction and white matter hyperintensity; 662, left ventricular hypertrophy.
  3. Plasma renin activity levels are expressed as median (interquartile range), and transformed into natural logarithm before analysis.
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