Figure 5
Myocardial messenger RNA expression levels of MMP-2 (a) and MMP-9 (b) in rats with CHF were determined by quantitative RT-PCR. The expression level of each sample was expressed relative to the expression level of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene. Data are mean±s.e.m. of five–seven rats. Group N, age-matched untreated rats; group V, CHF rats administered with vehicle; group T10, CHF rats treated with telmisartan (10 mg kg–1 day–1). The values are mean±s.e.m. **P<0.01 vs. group N; ##P<0.01 vs. group V.
