Table 4 Correlation coefficients between clinical characteristics and laboratory parameters of pre-eclamptic patients and their serum sFlt-1, PlGF levels and sFlt-1/PlGF ratio

From: Circulating angiogenic factors determined by electrochemiluminescence immunoassay in relation to the clinical features and laboratory parameters in women with pre-eclampsia

 

Serum sFlt-1 level

Serum PlGF level

Serum sFlt-1/PlGF ratio

Age

−0.01

−0.08

0.02

BMI at blood draw

−0.22

0.28

−0.29

Systolic blood pressure

0.31

−0.23

0.35

Diastolic blood pressure

0.35

−0.07

0.30

Gestational age at disease onset

−0.07

0.30

−0.21

Gestational age at blood draw

−0.07

0.28

−0.18

Gestational age at delivery

−0.25

0.40

−0.36

Fetal birth weight

−0.16

0.41

−0.30

Serum BUN level

0.52

−0.48

0.58

Serum creatinine level

0.57

−0.30

0.55

Serum bilirubin level

−0.11

0.22

−0.20

Serum AST activity

0.27

−0.05

0.21

Serum ALT activity

0.24

−0.01

0.19

Serum CRP level

−0.25

0.09

−0.22

Plasma VWF:Ag level

0.46

−0.10

0.35

Plasma fibronectin level

0.61

−0.30

0.55

Plasma malondialdehyde level

0.02

−0.09

0.01

Plasma cell-free fetal DNA level

0.47

−0.29

0.45

  1. Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; CRP, C-reactive protein; DNA, deoxyribonucleic acid; PlGF, placental growth factor; sFlt-1, soluble fms-like tyrosine kinase-1; VWF:Ag, von Willebrand factor antigen.
  2. Significant correlations are shown in bold.