Table 4 Effect of treatment on plasma PAI-1 antigen and Ang II

From: Role of angiotensin II in plasma PAI-1 changes induced by imidapril or candesartan in hypertensive patients with metabolic syndrome

Time

Imidapril

Candesartan

PAI-1 antigen (ng ml−1)

 Baseline

26.6±13.1

26.2±13.3

 Week 2

19.2±9.8*

21.1±11.1*

 Week 4

16.8±7.6**

25.3±13.7

 Week 8

18.1±8.1*

29.5±13.1

 Week 12

17.5±7.4**

31.9±12.6* °

 Week 16

17.3±7.5**

32.7±13.8** +

Ang II (pg ml−1)

 Baseline

29.8±7.8

28.9±7.2

 Week 2

17.2±4.1**

32.2±10.5°

 Week 4

15.5±3.7**

38.4±12.3* +

 Week 8

14.7±3.5**

46.7±16.4** +

 Week 12

14.8±3.4**

52.8±19.1** +

 Week 16

15.2±3.6**

53.1±20.5** +

  1. Abbreviations: Ang II, angiotensin II; PAI-1, plasminogen activator inhibitor-1.
  2. *P<0.05 vs. baseline; **P<0.01 vs. baseline; °P<0.05; +P<0.01 vs. imidapril.
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