Table 2 Echocardiographic parameters of DS/lean and DS/obese rats at 15 weeks of age

From: Cardiac remodeling and diastolic dysfunction in DahlS.Z-Leprfa/Leprfa rats: a new animal model of metabolic syndrome

Parameter

DS/lean

DS/obese

Heart rate (beats per min)

215±4

206±16

IVST (mm)

1.80±0.08

2.38±0.03*

LVPWT (mm)

1.79±0.06

2.32±0.04*

LVDd (mm)

6.56±0.08

6.94±0.21

LVDs (mm)

3.09±0.15

2.64±0.13

LVFS (%)

53.6±2.4

64.7±1.6*

LVEF (%)

81.7±1.9

90.9±1.0*

LV mass (mg)

742±32

1447±42*

RWT

0.53±0.02

0.64±0.02*

E/A

1.97±0.07

1.49±0.05*

DcT (ms)

42.8±2.5

52.9±1.9*

IRT (ms)

19.0±1.3

35.4±2.1*

Tei index

0.37±0.02

0.45±0.02*

  1. Abbreviations: Dct, deceleration time; DS, Dahl salt-sensitive; IRT, isovolumic relaxation time; IVST, interventricular septum thickness; LV mass, left ventricular mass; LVDd, LV end-diastolic; LVDs, LV end-systolic; LVEF, LV ejection fraction; LVFS, LV fractional shortening; LVPWT, LV posterior wall thickness; RWT, relative wall thickness.
  2. *P<0.05 vs. DS/lean rats.
  3. Data are means±s.e.m. for surviving animals (n=10 and 14 for DS/lean rats and DS/obese rats, respectively).