Table 3 Summary of organ weight and urinary protein/creatinine ratio

From: Aldosterone/NaCl-induced renal and cardiac fibrosis is modulated by TGF-β responsiveness of T cells

 

WT/con

Tg/con

WT/aldo

Tg/aldo

Significance (P<0.05)

Renal weight/tibia length

27.4±0.7

27.3±1.0

33.0±1.8

30.7±0.6

(1) WT/aldo vs. WT/con

(2) Tg/aldo vs. Tg/con

Heart weight/tibia length

7.9±0.2

7.8±0.4

9.3±0.4

8.2±0.3

WT/aldo vs. WT/con

Left ventricle weight/tibia length

5.5±0.1

5.3±0.2

6.5±0.4

5.7±0.3

WT/aldo vs. WT/con

Glomerluar injury score

1.5±0.1

1.6±0.2

1.5±0.1

1.7±0.1

 

Urinary protein/creatinine (mg mg−1)

0.6±0.1

2.4±0.5

1.2±0.2

4.2±0.8

(1) WT/aldo vs. WT/con

(2) Tg/con vs. WT/con

Plasma Urea concentration (mg dl−1)

35.2±1.4

44.6±10.9

28.8±2.4

32.4±0.3

 
  1. Abbreviations: aldo, aldosterone; con, control; Tg, transgenic; WT, wild type.
  2. N=4–6 animals per group.