Figure 3
Mean blood pressure, heart rate and sympathetic nerve activity after crossover administration of amlodipine or azelnidipine. Daily changes in mean blood pressure, heart rate, and LF/HF ratio before and after 1 week of treatment with (a, d, g) amlodipine (Amlo; 1.0 mg kg−1 per day) or (b, e, h) azelnidipine (Azel; 3.0 mg kg−1 per day) in Dahl salt-sensitive rats. Amlo (−), before treatment with Amlo; Amlo (+), after treatment with Amlo; Azel (−), before treatment with Azel; Azel (+), after treatment with Azel. (c) Average mean blood pressure. (f) Average heart rate. (i) Average LF/HF ratio. n=8 for each group. *P<0.05 vs. untreatment.
