Figure 4

Changes in renal function after chronic administration of amlodipine (Amlo) or azelnidipine (Azel) in Dahl salt-sensitive rats. Serum creatinine (a), urinary protein (b), urinary 8-OHdG (c) and urinary MDA (d). n=7 for each group. *P<0.05 vs. DN; †P<0.05 vs. DH; ‡P<0.05 vs. DH-Amlo. DN, control normotensive Dahl salt-sensitive rats; DH, hypertensive Dahl salt-sensitive rats; MDA, malondialdehyde; 8-OHdG, 8-hydroxydeoxyguanosine.