Table 2 Pathophysiological data for renal denervated Dahl salt-sensitive rats treated with amlodipine or azelnidipine

From: Azelnidipine attenuates glomerular damage in Dahl salt-sensitive rats by suppressing sympathetic nerve activity

Group

Amlo+renal denervation (n=7)

Azel+renal denervation (n=7)

BW (g)

328±7

324±8

SBP (mm Hg)

159±6

153±7

HR (b.p.m.)

404±9

379±10

Kidney NE (ng g−1 tissue)

0.16±0.09

0.19±0.08

S-Cre (mg dl−1)

0.44±0.07

0.52±0.02

U-Pro (mg g−1 U-Cre)

4.4±0.5

5.1±0.9

Glomerular injury score

1.2±0.5

1.1±0.5

  1. Data are presented as mean±s.e.m.
  2. Amlo, amlodipine; Azel, azelnidipine; BW, body weight; HR, heart rate; NE, norepinephrine concentration; SBP, systolic blood pressure. S-Cre, serum creatinine; U-Cre, urinary creatinine; U-Pro, urinary protein.
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