Table 3 Multiple regression analysis for E/E′ and related parameters

From: The balance of fetuin-A and osteoprotegerin is independently associated with diastolic dysfunction in hemodialysis patients

	With baPWV			Without baPWV
	β	t	P	β	t	P
Model 1
Fetuin-A	−0.325	−2.308	0.026	−0.298	−2.230	0.031
Age	0.168	1.181	0.244	0.096	1.181	0.244
Sex (M=1)	−0.268	−1.953	0.057	−0.261	−1.953	0.057
Duration of dialysis	0.067	0.468	0.642	0.089	0.468	0.642
Mean BP	−0.151	−1.062	0.294	−0.098	−1.062	0.294
Heart rate	−0.990	−0.638	0.527	−0.015	−0.638	0.527
BMI	−0.121	−0.852	0.399	−0.055	−0.852	0.399
Hemoglobin	−0.020	−0.135	0.894	−0.005	−0.135	0.894
Smoking	0.037	0.260	0.796	−0.004	0.260	0.796
Medication for hypertension	0.171	1.211	0.232	0.148	1.211	0.232
Medication for diabetes	0.140	0.969	0.338	0.098	0.969	0.338
Medication for dyslipidemia	0.192	1.160	0.080	0.251	1.160	0.080
Prior coronary artery disease	0.062	0.468	0.642	0.038	0.468	0.642
BNP	0.252	1.892	0.059	0.339	2.537	0.015
baPWV	0.344	2.551	0.015	—	—	—
Model 2
Osteoprotegerin	0.367	2.563	0.010	0.404	2.995	0.004
Age	0.148	1.043	0.303	0.080	1.043	0.573
Sex (M=1)	−0.258	−2.088	0.063	−0.263	−2.005	0.068
Duration of dialysis	−0.204	−1.151	0.256	−0.178	−1.151	0.303
Mean BP	−0.153	−1.092	0.281	−0.071	−1.092	0.620
Heart rate	−0.151	−1.068	0.291	−0.124	−1.068	0.369
BMI	−0.053	−0.373	0.711	−0.019	−0.373	0.891
Hemoglobin	−0.050	−0.346	0.731	−0.005	−0.346	0.973
Smoking	0.052	0.368	0.715	0.122	0.368	0.380
Medication for hypertension	0.207	1.508	0.139	0.184	1.508	0.171
Medication for diabetes	0.244	1.789	0.080	0.186	1.789	0.178
Medication for dyslipidemia	0.204	1.484	0.145	0.138	1.484	0.321
Prior coronary artery disease	0.153	1.098	0.278	0.104	1.098	0.450
BNP	0.282	2.000	0.052	0.263	2.000	0.059
baPWV	0.273	1.432	0.159	—	—	—
Model 3
OPG/fetuin-A	0.295	2.071	0.044	0.275	1.934	0.048
Age	0.162	1.114	0.303	0.105	0.737	0.465
Sex (M=1)	−0.243	−1.810	0.068	−0.258	−1.888	0.058
Duration of dialysis	−0.094	−0.547	0.256	−0.012	−0.073	0.942
Mean BP	−0.138	−0.960	0.281	−0.086	−0.608	0.546
Heart rate	−0.143	−0.966	0.291	−0.086	−0.592	0.557
BMI	−0.068	−0.470	0.711	−0.016	−0.112	0.911
Hemoglobin	−0.053	−0.353	0.731	−0.050	−0.352	0.727
Smoking	0.067	0.462	0.715	0.020	0.141	0.888
Medication for hypertension	0.199	1.413	0.139	0.178	1.307	0.198
Medication for diabetes	0.205	1.459	0.120	0.165	1.200	0.237
Medication for dyslipidemia	0.243	1.742	0.145	0.207	1.520	0.136
Prior coronary artery disease	0.127	0.891	0.278	0.101	0.728	0.470
BNP	0.297	2.189	0.034	0.311	2.213	0.032
baPWV	0.284	1.905	0.063	—	—	—

Abbreviations: β, β coefficient; baPWV, brachial–ankle pulse wave velocity; BMI, body mass index; BNP, brain natriuretic peptide; BP, blood pressure; OPG, osteoprotegerin.
Model 1, F ratio=6.243; r²=0.221 (P=0.004) with baPWV, F ratio=6.203; r²=0.220 (P=0.004) without baPWV.
Model 2, F ratio=6.571; r²=0.219 (P=0.004) with baPWV, F ratio=6.176; r²=0.210 (P=0.008) without baPWV.
Model 3, F ratio=4.780; r²=0.178 (P=0.013) with baPWV, F ratio=4.782; r²=0.188 (P=0.010) without baPWV.

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Table 3 Multiple regression analysis for E/E′ and related parameters

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