Table 1 Baseline characteristics of HOMED-BP participants

From: Cardiovascular outcomes in the first trial of antihypertensive therapy guided by self-measured home blood pressure

Characteristic

Usual control

Tight control

ACEIs

ARBs

CCBs

Number

1759

1759

1172

1175

1171

Mean characteristic (s.d.)

 Age (years)

59.6 (9.9)

59.6 (10.2)

59.8 (10.0)

59.5 (10.1)

59.5 (10.1)

 Body mass index (kg m−2)

24.4 (3.5)

24.4 (3.4)

24.5 (3.6)

24.5 (3.4)

24.2 (3.3)

 Home measurements

Systolic pressure

151.7 (12.6)*

151.5 (12.3)*

151.6 (12.5)*

151.6 (12.4)*

151.6 (12.6)*

Diastolic pressure

89.9 (10.3)

90.0 (9.8)

89.8 (10.0)

89.8 (10.1)

90.1 (9.9)

Heart rate

69.4 (9.5)*

68.8 (9.4)*

69.0 (9.2)*

69.0 (9.5)*

69.1 (9.5)*

 Clinic measurements

Systolic pressure

154.1 (17.5)

154.3 (17.5)

153.9 (17.5)

153.9 (17.1)

154.8 (17.9)

Diastolic pressure

90.0 (12.1)

90.4 (12.2)

89.9 (12.4)

90.1 (11.7)

90.6 (12.5)

Heart rate

74.9 (11.8)

75.0 (12.0)

75.3 (11.9)

74.6 (12.1)

75.0 (11.7)

 Biochemical measurements

Plasma glucose (mmol l−1)

5.88 (1.78)

5.81 (1.65)

5.88 (1.73)

5.85 (1.77)

5.80 (1.63)

Serum total cholesterol (mmol l−1)

5.46 (0.93)

5.45 (0.90)

5.44 (0.88)

5.50 (0.95)

5.42 (0.92)

Number with characteristic (%)

 Women

883 (50)

880 (50)

589 (50)

588 (50)

586 (50)

 Current smoking

381 (22)

389 (22)

250 (21)

266 (23)

255 (22)

 Past smoker

293 (17)

305 (17)

184 (16)

199 (17)

216 (18)

 Current habitual drinking

857 (49)

874 (50)

568 (48)

584 (50)

579 (49)

 Past drinker

80 (5)

84 (5)

46 (4)

67 (6)

51 (4)

 Diabetes mellitus

271 (15)

267 (15)

181 (15)

191 (16)

166 (14)

 Use of antidiabetic drugs

141 (8)

155 (9)

96 (8)

101 (9)

99 (8 )

 Hypercholesterolemia

599 (34)

591 (34)

392 (33)

410 (35)

388 (33)

 Previous cardiovascular disease

47 (3)

59 (3)

34 (3)

41 (3)

31 (3)

  1. Abbreviations: ACEIs, angiotensin converting enzyme inhibitors; ARBs, angiotensin receptor blockers; CCBs, calcium channel blockers; HOMED-BP, Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure.
  2. Home blood pressure was the average of the morning readings over 5 days immediately preceding the clinic visit. The clinic blood pressure was the average of two consecutive measurements. Diabetes mellitus is a fasting plasma glucose of 7.0 mmol l−1 (126 mg dl−1) or more, or an HbA1c of 6.5% or more, or treatment with oral antidiabetic drugs or insulin. Hypercholesterolemia is total serum cholesterol of 5.69 mmol l−1 (220 mg dl−1) or more, a history of hypercholesterolemia, or taking lipid-lowering drugs. Baseline characteristics did not differ between randomized groups (P⩾0.10) with the exception of a trend for heart rate at home between usual and tight control group (P=0.056). Asterisks denote significant differences (P<0.0001) between the home and conventional measurements of blood pressure and heart rate.
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