Figure 2

Offspring systolic and diastolic blood pressure from 4 weeks until 24 weeks as a consequence of maternal low-protein diet (MLPD). (a) Systolic blood pressure of female mice. (b) Diastolic blood pressure of female mice. (c) Systolic blood pressure of male mice. (d) Diastolic blood pressure of male mice. * denotes significant difference (P<0.05) between control and moderate MLPD groups for diet and sex as main factors by repeated measure (RM) two-way analysis of variance (ANOVA). # denotes significant difference (P<0.05) between control and severe groups for diet and sex as main factors by RM two-way ANOVA. (e) and (f) show comparison of males and females systolic and diastolic blood pressures in three diet group as analyzed by multiple regression and RM two-way ANOVA. Black lines denote female and gray lines denote male groups. Solid lines, stippled lines and dotted lines denotes control, moderate MLPD and severe MLPD groups, respectively. a, b and c denotes significant difference (P<0.05) between male and female subjects, and * denotes a significant interaction between sex × diet on systolic (e) and diastolic (f) as determined by RM two-way ANOVA with sex and diet as main factors.