Table 2 Echocardiographic parameters with M-mode measurements for the WKY and SHR groups

From: Early regression of left ventricular hypertrophy after treatment with esmolol in an experimental rat model of primary hypertension

 

WKY (n=9)

SHR (n=8)

SHR-E (n=8)

SHR-N (n=8)

P-values ANOVA

LVIDd (cm)

0.50±0.05

0.40±0.06†

0.57±0.15∥

0.63±0.13*,∥

0.002

LVIDs (cm)

0.22±0.06

0.10±0.04‡

0.22±0.14

0.16±0.04*,§

0.023

IVSd (cm)

0.27±0.05

0.40±0.05‡

0.26±0.04#

0.30±0.01∥,**

<0.001

PWd (cm)

0.28±0.06

0.37±0.05†

0.28±0.07§

0.31±0.02§

0.006

LVM (g)

1.48±0.25

1.87±0.20†

1.57±0.10∥

2.02±0.34†,**

<0.001

LVMI (mg g−1)

3.41±0.65

4.71±0.62‡

3.95±0.33*,∥

4.82±0.51‡,††

<0.001

RWT

1.13±0.23

2.00±0.43‡

1.06±0.5#

1.00±0.20#

<0.001

EF (%)

78.64±9.03

93.08±4.69†

85.52±10.93

92.10±4.86†

0.005

FS (%)

55.01±11.22

74.99±8.80†

64.51±14.81

73.31±9.63†

0.007

  1. Abbreviations: ANOVA, analysis of variance; EF, left ventricular ejection fraction; FS, left ventricular fractional shortening; IVSd, interventricular septal end diastolic thickness; LVIDd, left ventricular end diastolic diameter; LVIDs, left ventricular end systolic diameter; LVM, left ventricular mass; LVMI, left ventricular mass index; PWd, left ventricular posterior wall diastolic thickness; RWT, relative wall thickness; SHR, spontaneously hypertensive rats treated with vehicle; SHR-E, spontaneously hypertensive rats treated with esmolol; SHR-N, spontaneously hypertensive rats treated with nitroglycerin.
  2. Statistically significant differences between WKY, SHR, SHR-E and SHR-N are shown (*P<0.05 vs. WKY; †P<0.01 vs. WKY; ‡P<0.001 vs. WKY; §P<0.05 vs. SHR; ∥P<0.01 vs. SHR; #P<0.001 vs. SHR; **P<0.05 vs. SHR-E; ††P<0.01 vs. SHR-E). Values are given as mean±s.d. ANOVA, LVIDd, LVIDs, IVSd, PWd, LVM, LVMI, RWT, EF, FS.
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