Table 1 Clinical characteristics of study participants (GA <35+0, N=130) grouped as healthy controls and hypertensive patients by diagnosis. Continuous variables are reported as Median (IQR) and categorical variables are reported as N (%)
From: Evaluation of a rapid and simple placental growth factor test in hypertensive disorders of pregnancy
Control (n=27) | GHT (n=18) | CHT (n=25) | PE (n=23) | HELLP (n=20) | SIPE (n=17) | |
|---|---|---|---|---|---|---|
Maternal age (years) | 31 (29–34) | 34 (29–35) | 34 (30–36) | 33 (30–37) | 30 (28–33) | 34 (32–36) |
Pre-gestational BMI (kg m−2) | 21.4 (19.4–24) | 25.9 (23.1–30.8)** | 31.4 (26.1–35.9)** | 25.6 (22.4–29.6)* | 23.9 (22.2–33.5)* | 24.4 (21.9–30)* |
Primiparas (%) | 8 (29.6) | 12 (66.7)* | 13 (52) | 12 (52.2) | 16 (80)** | 8 (47.1) |
Systolic blood pressure at blood draw (mm Hg) | 110 (109–120) | 154 (146–158)** | 143 (140–147)** | 169 (160–178)** | 170 (165–172)** | 164 (151–170)** |
Diastolic blood pressure at blood draw (mm Hg) | 70 (66–75) | 96 (94–100)** | 89 (80–94)** | 109 (100–114)** | 110 (95–114)** | 104 (96–112)** |
GA at disease onset (weeks) | NA | 28 (26–33) | NA | 30 (27–32) | 30 (28–32) | 30 (28–31) |
GA at blood draw (weeks) | 31 (29–33) | 33 (31–34) | 33 (30–34) | 31 (28–33) | 31 (28–32) | 31 (28–32) |
GA at delivery (weeks) | 39 (38–40) | 38 (36–39) | 37 (34–38)** | 31 (28–34)** | 31 (28–32)** | 32 (30–36)** |
Blood draw to delivery time interval (days) | 55 (40–70) | 29 (21–51)* | 21 (4–45)** | 1 (0–3)** | 0 (0–1)** | 8 (3–25)** |
Premature birth (%) | 3 (11.1) | 7 (38.9) | 11 (44)* | 22 (95.7)** | 20 (100)** | 14 (82.4)** |
Fetal birthweight (grams) | 3270 (3100–3560) | 3280 (2150–3860) | 2710 (2130–3370)* | 1330 (990–1740)** | 1265 (940–1575)** | 1750 (1100–2560)** |
Fetal growth restriction (%) | 0 (0) | 3 (16.7) | 2 (8) | 10 (43.5)** | 6 (30)* | 5 (29.4)* |
Early-onset PE (%) | 0 (0) | 0 (0) | 0 (0) | 21 (91.3)** | 17 (85)** | 16 (94.1)** |
Severe PE (%) | 0 (0) | 0 (0) | 0 (0) | 22 (95.7)** | 20 (100)** | 11 (64.7)** |
