Table 1 Change in beat-to-beat blood pressure variability in the, VLF, LF and HF domain (expressed as % of baseline values) after i.v. administration of low and high dose of carvedilol, nebivolol, atenolol and verapamil in SAD rats
Atenolol | Carvedilol | Nebivolol | Verapamil | |||||
|---|---|---|---|---|---|---|---|---|
0.3 mg kg − 1 | 3 mg kg − 1 | 0.1 mg kg − 1 | 1 mg kg − 1 | 0.3 mg kg − 1 | 3 mg kg − 1 | 0.3 mg kg − 1 | 3 mg kg − 1 | |
Total power density | −3.8±5.4 | 8.6±5.8 | −39.7±8.6*,# | −56.3±5.9*,§ | −21.4±3.3 | −28.9±5.6* | −11.3±2.7 | −58.7±5.8*,§ |
VLF | 3.9±3.5 | 11.8±2.9 | −41.4±8.6* | −54.2±5.1* | −17.52±10.3 | −35.9±8.8* | −14.2±3.6 | −57.9±6.3* |
LF | −1.3±2 | 3.3±9.5 | −39.9±8.4*,§,# | −60.2±4.9*,§ | −11.9±4.9 | −29.1±6.5* | −13.2±3.5 | −59.1±5*,§ |
HF | −1.3±2.7 | 8.8±6.2 | −26.1±9.1 | −52.7±7*,§ | −7.6±8 | −22.9±7.2* | −11.1±1.9 | −52.2±5.5*,§ |
