Table 1 Information of the analyzed SNPs of the ADD1 and GNB3 genes

From: Association between genetic variants of the ADD1 and GNB3 genes and blood pressure response to the cold pressor test in a Chinese Han population: the GenSalt Study

Gene

SNP

Chr

Physical location

Region in gene

Alleles (major/minor)

MAF

HW P-value

ADD1

rs4690002

4

281 1038

5′ Flanking

C/T

0.44

0.60

 

rs12503220

4

281 9940

intron 1

G/A

0.14

0.70

 

rs1263359

4

283 1824

intron 1

T/C

0.43

0.93

 

rs17833172

4

283 8312

intron 1

G/A

0.04

0.21

 

rs3775067

4

285 8420

intron 4

C/T

0.34

0.77

 

rs4961

4

287 6505

exon 9(missense)

T/G

0.48

0.20

 

rs4963

4

288 6560

exon12(missense)

G/C

0.48

0.54

GNB3

rs4963516

12

681 8289

5′ flanking

A/C

0.32

0.12

 

rs1129649

12

681 8729

5′ flanking

T/C

0.31

0.61

 

rs3213431

12

681 8789

5′ flanking

T/C

0.11

0.82

 

rs2301339

12

682 4885

intron 9

G/A

0.45

0.66

 

rs5446

12

682 6723

3′ UTR

C/T

0.20

0.68

  1. Abbreviations: ADD1, α-adducin; GNB3, guanine nucleotide binding protein (G protein) β-polypeptide 3; H–W, Hardy–Weinberg equilibrium test; MAF, minor allele frequency; SNP, single-nucleotide polymorphism.
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